Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin

Eukaryotic pre-mRNA is processed by a large multiprotein complex to accurately cleave the 3′ end, and to catalyse the addition of the poly(A) tail. Within this cleavage and polyadenylation specificity factor (CPSF) machinery, the CPSF73/CPSF3 endonuclease subunit directly contacts both CPSF100/CPSF2...

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Detalles Bibliográficos
Autores principales: Thore, Stéphane, Raoelijaona, Finaritra, Talenton, Vincent, Fribourg, Sébastien, Mackereth, Cameron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688271/
https://www.ncbi.nlm.nih.gov/pubmed/37989222
http://dx.doi.org/10.1098/rsob.230221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688271/
https://www.ncbi.nlm.nih.gov/pubmed/37989222
http://dx.doi.org/10.1098/rsob.230221

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