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RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcripts
Alpha-synuclein (SNCA) accumulation plays a central role in the pathogenesis of Parkinson's disease. Determining and interfering with the mechanisms that control SNCA expression is one approach to limiting disease progression. Currently, most of our understanding of SNCA regulation is protein-b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688287/ https://www.ncbi.nlm.nih.gov/pubmed/37989221 http://dx.doi.org/10.1098/rsob.230158 |