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RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcripts

Alpha-synuclein (SNCA) accumulation plays a central role in the pathogenesis of Parkinson's disease. Determining and interfering with the mechanisms that control SNCA expression is one approach to limiting disease progression. Currently, most of our understanding of SNCA regulation is protein-b...

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Detalles Bibliográficos
Autores principales: Kattan, Fedon-Giasin, Koukouraki, Pelagia, Anagnostopoulos, Athanasios K., Tsangaris, George T., Doxakis, Epaminondas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688287/
https://www.ncbi.nlm.nih.gov/pubmed/37989221
http://dx.doi.org/10.1098/rsob.230158