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Sirtuin 1 alleviates alcoholic liver disease by inhibiting HMGB1 acetylation and translocation

BACKGROUND: Alcoholic liver disease (ALD) encompasses a spectrum of liver disorders resulting from prolonged alcohol consumption and is influenced by factors such as oxidative stress, inflammation, and apoptosis. High Mobility Group Box 1 (HMGB1) plays a pivotal role in ALD due to its involvement in...

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Detalles Bibliográficos
Autores principales: Fu, Juan, Deng, Wei, Ge, Jun, Fu, Shengqi, Li, Panpan, Wu, Huazhi, Wang, Jiao, Gao, Yi, Gao, Hui, Wu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688304/
https://www.ncbi.nlm.nih.gov/pubmed/38034869
http://dx.doi.org/10.7717/peerj.16480