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Epitope-dependent effect of long-term cART on maintenance and recovery of HIV-1-specific CD8(+) T cells

The frequency of HIV-1-specific T cells is reduced and their functional ability remains impaired in people living with HIV-1 (PLWH) under combined antiretroviral therapy (cART). However, no studies have yet reported on T-cell responses to large numbers of well-characterized HIV-1 epitopes before and...

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Detalles Bibliográficos
Autores principales: Kuse, Nozomi, Gatanaga, Hiroyuki, Zhang, Yu, Chikata, Takayuki, Oka, Shinichi, Takiguchi, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688310/
https://www.ncbi.nlm.nih.gov/pubmed/37877716
http://dx.doi.org/10.1128/jvi.01024-23