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Identification of host dependency factors involved in SARS-CoV-2 replication organelle formation through proteomics and ultrastructural analysis

Positive-strand RNA viruses subvert the cellular endomembrane system for the generation of distinct compartments termed replication organelles (ROs) that harbor the site where viral RNAs are generated. In this study, we corroborate that the SARS-CoV-2 non-structural proteins 3 and 4 (nsp3 and nsp4)...

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Detalles Bibliográficos
Autores principales: Pahmeier, Felix, Lavacca, Teresa-Maria, Goellner, Sarah, Neufeldt, Christopher J., Prasad, Vibhu, Cerikan, Berati, Rajasekharan, Sreejith, Mizzon, Giulia, Haselmann, Uta, Funaya, Charlotta, Scaturro, Pietro, Cortese, Mirko, Bartenschlager, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688318/
https://www.ncbi.nlm.nih.gov/pubmed/37905840
http://dx.doi.org/10.1128/jvi.00878-23