Cargando…
Identification of host dependency factors involved in SARS-CoV-2 replication organelle formation through proteomics and ultrastructural analysis
Positive-strand RNA viruses subvert the cellular endomembrane system for the generation of distinct compartments termed replication organelles (ROs) that harbor the site where viral RNAs are generated. In this study, we corroborate that the SARS-CoV-2 non-structural proteins 3 and 4 (nsp3 and nsp4)...
Autores principales: | Pahmeier, Felix, Lavacca, Teresa-Maria, Goellner, Sarah, Neufeldt, Christopher J., Prasad, Vibhu, Cerikan, Berati, Rajasekharan, Sreejith, Mizzon, Giulia, Haselmann, Uta, Funaya, Charlotta, Scaturro, Pietro, Cortese, Mirko, Bartenschlager, Ralf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688318/ https://www.ncbi.nlm.nih.gov/pubmed/37905840 http://dx.doi.org/10.1128/jvi.00878-23 |
Ejemplares similares
-
A Versatile Reporter System To Monitor Virus-Infected Cells and Its Application to Dengue Virus and SARS-CoV-2
por: Pahmeier, Felix, et al.
Publicado: (2021) -
Replication-Independent Generation and Morphological Analysis of Flavivirus Replication Organelles
por: Goellner, Sarah, et al.
Publicado: (2020) -
A Non-Replicative Role of the 3′ Terminal Sequence of the Dengue Virus Genome in Membranous Replication Organelle Formation
por: Cerikan, Berati, et al.
Publicado: (2020) -
A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle
por: Płaszczyca, Anna, et al.
Publicado: (2019) -
Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formation
por: Twu, Woan-Ing, et al.
Publicado: (2021)