African swine fever virus B175L inhibits the type I interferon pathway by targeting STING and 2′3′-cGAMP

Type I interferon (IFN)-mediated responses operate a pivotal role in the first line of host immune defense against viruses. Upon DNA virus infection, DNA sensing cyclic GMP-AMP synthase-STING signal pathway is a key event in the IFN-mediated antiviral response and also a target of viral immune evasi...

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Detalles Bibliográficos
Autores principales: Ranathunga, Lakmal, Dodantenna, Niranjan, Cha, Ji-Won, Chathuranga, Kiramage, Chathuranga, W. A. Gayan, Weerawardhana, Asela, Subasinghe, Ashan, Haluwana, D. K., Gamage, Nuwan, Lee, Jong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688321/
https://www.ncbi.nlm.nih.gov/pubmed/37902401
http://dx.doi.org/10.1128/jvi.00795-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688321/
https://www.ncbi.nlm.nih.gov/pubmed/37902401
http://dx.doi.org/10.1128/jvi.00795-23

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