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Vaccine-induced antibody Fc-effector functions in humans immunized with a combination Ad26.RSV.preF/RSV preF protein vaccine

An Ad26.RSV.preF/RSV preF protein combination vaccine demonstrated 80.0% vaccine efficacy for the prevention of respiratory syncytial virus (RSV)-mediated lower respiratory tract disease in a phase 2b study. In addition to neutralizing antibodies, Fc-effector functions are associated with protective...

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Detalles Bibliográficos
Autores principales: Bartsch, Yannic C., Cizmeci, Deniz, Yuan, Dansu, Mehta, Nickita, Tolboom, Jeroen, De Paepe, Els, van Heesbeen, Roy, Sadoff, Jerald, Comeaux, Christy A., Heijnen, Esther, Callendret, Benoit, Alter, Galit, Bastian, Arangassery Rosemary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688327/
https://www.ncbi.nlm.nih.gov/pubmed/37902399
http://dx.doi.org/10.1128/jvi.00771-23