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Progranulin and GPNMB: interactions in endo-lysosome function and inflammation in neurodegenerative disease
BACKGROUND: Alterations in progranulin (PGRN) expression are associated with multiple neurodegenerative diseases (NDs), including frontotemporal dementia (FTD), Alzheimer’s disease (AD), Parkinson’s disease (PD), and lysosomal storage disorders (LSDs). Recently, the loss of PGRN was shown to result...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688479/ https://www.ncbi.nlm.nih.gov/pubmed/38037070 http://dx.doi.org/10.1186/s12974-023-02965-w |