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ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells

OBJECTIVE: Osteosarcoma is a rare primary malignant tumor of the bone characterized by poor survival rates, owing to its unclear pathogenesis. Rho GTPase-activating protein 44 (ARHGAP44), which belongs to the Rho GTPase-activating protein family, has promising applications in the targeted therapy of...

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Detalles Bibliográficos
Autores principales: Li, Shizhe, Xue, Jiancheng, Zhang, He, Shang, Guanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688487/
https://www.ncbi.nlm.nih.gov/pubmed/38031136
http://dx.doi.org/10.1186/s13018-023-04406-z