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Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells
BACKGROUND: Chromobox protein homolog 7 (CBX7), a member of the Polycomb repressor complex, is a potent epigenetic regulator and gene silencer. Our group has previously reported that CBX7 functions as a tumor suppressor in ovarian cancer cells and its loss accelerated formation of carcinomatosis and...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688490/ https://www.ncbi.nlm.nih.gov/pubmed/38037081 http://dx.doi.org/10.1186/s13048-023-01312-0 |