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STmut: a framework for visualizing somatic alterations in spatial transcriptomics data of cancer

Spatial transcriptomic technologies, such as the Visium platform, measure gene expression in different regions of tissues. Here, we describe new software, STmut, to visualize somatic point mutations, allelic imbalance, and copy number alterations in Visium data. STmut is tested on fresh-frozen Visiu...

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Detalles Bibliográficos
Autores principales: Chen, Limin, Chang, Darwin, Tandukar, Bishal, Deivendran, Delahny, Pozniak, Joanna, Cruz-Pacheco, Noel, Cho, Raymond J., Cheng, Jeffrey, Yeh, Iwei, Marine, Chris, Bastian, Boris C., Ji, Andrew L., Shain, A. Hunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688493/
https://www.ncbi.nlm.nih.gov/pubmed/38037084
http://dx.doi.org/10.1186/s13059-023-03121-6