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A seed expansion-based method to identify essential proteins by integrating protein–protein interaction sub-networks and multiple biological characteristics
BACKGROUND: The identification of essential proteins is of great significance in biology and pathology. However, protein–protein interaction (PPI) data obtained through high-throughput technology include a high number of false positives. To overcome this limitation, numerous computational algorithms...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688502/ https://www.ncbi.nlm.nih.gov/pubmed/38036960 http://dx.doi.org/10.1186/s12859-023-05583-8 |