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A seed expansion-based method to identify essential proteins by integrating protein–protein interaction sub-networks and multiple biological characteristics

BACKGROUND: The identification of essential proteins is of great significance in biology and pathology. However, protein–protein interaction (PPI) data obtained through high-throughput technology include a high number of false positives. To overcome this limitation, numerous computational algorithms...

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Detalles Bibliográficos
Autores principales: Zhao, He, Liu, Guixia, Cao, Xintian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688502/
https://www.ncbi.nlm.nih.gov/pubmed/38036960
http://dx.doi.org/10.1186/s12859-023-05583-8

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