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Preferential selection of viral escape mutants by CD8(+) T cell ‘sieving’ of SIV reactivation from latency
HIV rapidly rebounds after interruption of antiretroviral therapy (ART). HIV-specific CD8(+) T cells may act to prevent early events in viral reactivation. However, the presence of viral immune escape mutations may limit the effect of CD8(+) T cells on viral rebound. Here, we studied the impact of C...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688670/ https://www.ncbi.nlm.nih.gov/pubmed/38032851 http://dx.doi.org/10.1371/journal.ppat.1011755 |