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The indole motif is essential for the antitrypanosomal activity of N(5)-substituted paullones

Severe infections with potentially fatal outcomes are caused by parasites from the genera Trypanosoma and Leishmania (class Kinetoplastea). The diseases affect people of remote areas in the tropics and subtropics with limited access to adequate health care. Besides insufficient diagnostics, treatmen...

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Detalles Bibliográficos
Autores principales: Ihnatenko, Irina, Müller, Marco J., Orban, Oliver C. F., Lindhof, Jens C., Benítez, Diego, Ortíz, Cecilia, Dibello, Estefanía, Seidl, Leonardo L., Comini, Marcelo A., Kunick, Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688702/
https://www.ncbi.nlm.nih.gov/pubmed/38032881
http://dx.doi.org/10.1371/journal.pone.0292946