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Single-cell sequencing, genetics, and epigenetics reveal mesenchymal stem cell senescence in osteoarthritis (Review)

Osteoarthritis (OA) is a chronic joint disease characterized by articular cartilage degeneration, secondary bone hyperplasia, inadequate extracellular matrix synthesis and degeneration of articular cartilage. Mesenchymal stem cells (MSCs) can self-renew and undergo multidirectional differentiation;...

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Detalles Bibliográficos
Autores principales: Tan, Dunyong, Huang, Zeqi, Zhao, Zhe, Chen, Xiaoqiang, Liu, Jianquan, Wang, Daping, Deng, Zhiqin, Li, Wencui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688769/
https://www.ncbi.nlm.nih.gov/pubmed/37937669
http://dx.doi.org/10.3892/ijmm.2023.5326