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Development of a novel medium throughput flow-cytometry based micro-neutralisation test for SARS-CoV-2 with applications in clinical vaccine trials and antibody screening

Quantifying neutralising capacity of circulating SARS-COV-2 antibodies is critical in evaluating protective humoral immune responses generated post-infection/post-vaccination. Here we describe a novel medium-throughput flow cytometry-based micro-neutralisation test to evaluate Neutralising Antibody...

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Detalles Bibliográficos
Autores principales: O’Reilly, Sophie, Kenny, Grace, Alrawahneh, Tamara, Francois, Nathan, Gu, Lili, Angeliadis, Matthew, de Masson d’Autume, Valentin, Garcia Leon, Alejandro, Feeney, Eoin R., Yousif, Obada, Cotter, Aoife, de Barra, Eoghan, Horgan, Mary, Mallon, Patrick W. G., Gautier, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688860/
https://www.ncbi.nlm.nih.gov/pubmed/38033116
http://dx.doi.org/10.1371/journal.pone.0294262