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Bone-derived PDGF-BB drives brain vascular calcification in male mice

Brain vascular calcification is a prevalent age-related condition often accompanying neurodegenerative and neuroinflammatory diseases. The pathogenesis of large-vessel calcifications in peripheral tissue is well studied, but microvascular calcification in the brain remains poorly understood. Here, w...

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Detalles Bibliográficos
Autores principales: Wang, Jiekang, Fang, Ching-Lien, Noller, Kathleen, Wei, Zhiliang, Liu, Guanqiao, Shen, Ke, Song, Kangping, Cao, Xu, Wan, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688993/
https://www.ncbi.nlm.nih.gov/pubmed/37815871
http://dx.doi.org/10.1172/JCI168447