CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity

Understanding the intricate dynamics between adoptively transferred immune cells and the brain tumor immune microenvironment (TIME) is crucial for the development of effective T cell–based immunotherapies. In this study, we investigated the influence of the TIME and chimeric antigen receptor (CAR) d...

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Detalles Bibliográficos
Autores principales: Haydar, Dalia, Ibañez-Vega, Jorge, Crawford, Jeremy Chase, Chou, Ching-Heng, Guy, Clifford S., Meehl, Michaela, Yi, Zhongzhen, Perry, Scott, Laxton, Jonathan, Cunningham, Trevor, Langfitt, Deanna, Vogel, Peter, DeRenzo, Christopher, Gottschalk, Stephen, Roussel, Martine F., Thomas, Paul G., Krenciute, Giedre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689147/
https://www.ncbi.nlm.nih.gov/pubmed/37971169
http://dx.doi.org/10.1158/2767-9764.CRC-23-0424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689147/
https://www.ncbi.nlm.nih.gov/pubmed/37971169
http://dx.doi.org/10.1158/2767-9764.CRC-23-0424

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