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Metabolomic profiles, polygenic risk scores and risk of rheumatoid arthritis: a population-based cohort study in the UK Biobank

OBJECTIVE: To investigate the relationship between metabolomic profiles, genome-wide polygenic risk scores (PRSs) and risk of rheumatoid arthritis (RA). METHODS: 143 nuclear magnetic resonance-based plasma metabolic biomarkers were measured among 93 800 participants in the UK Biobank. The Cox regres...

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Detalles Bibliográficos
Autores principales: Fang, Xin-Yu, Zhang, Jie, Qian, Ting-Ting, Gao, Peng, Wu, Qing, Fang, Quan, Ke, Su-Su, Huang, Rong-Gui, Zhang, Heng-Chuan, Qiao, Ni-Ni, Fan, Yin-Guang, Ye, Dong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689387/
https://www.ncbi.nlm.nih.gov/pubmed/38035758
http://dx.doi.org/10.1136/rmdopen-2023-003560