Inhibition of bradykinin in SARS-CoV-2 infection: a randomised, double-blind trial of icatibant compared with placebo (ICASARS)

SARS-CoV-2 binds to ACE2 receptors and enters cells. The symptoms are cough, breathlessness, loss of taste/smell and X-ray evidence of infiltrates on chest imaging initially caused by oedema, and subsequently by a lymphocytic pneumonitis. Coagulopathy, thrombosis and hypotension occur. Worse disease...

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Detalles Bibliográficos
Autores principales: Bailey, Melanie, Linden, Dermot, Earley, Olivia, Guo Parke, Hong, McAuley, Daniel Francis, Peto, Tunde, Taggart, Cliff, Kidney, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Respiratory Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689398/
https://www.ncbi.nlm.nih.gov/pubmed/38035747
http://dx.doi.org/10.1136/bmjopen-2023-074726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689398/
https://www.ncbi.nlm.nih.gov/pubmed/38035747
http://dx.doi.org/10.1136/bmjopen-2023-074726

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