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Natural product rhynchophylline prevents stress-induced hair graying by preserving melanocyte stem cells via the β2 adrenergic pathway suppression

Norepinephrine (NA), a stress hormone, can accelerate hair graying by binding to β2 adrenergic receptors (β(2)AR) on melanocyte stem cells (McSCs). From this, NA-β(2)AR axis could be a potential target for preventing the stress effect. However, identifying selective blockers for β(2)AR has been a ke...

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Detalles Bibliográficos
Autores principales: Li, Xinxin, Shi, Runlu, Yan, Lingchen, Chu, Weiwei, Sun, Ruishuang, Zheng, Binkai, Wang, Shuai, Tan, Hui, Wang, Xusheng, Gao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689686/
https://www.ncbi.nlm.nih.gov/pubmed/38036925
http://dx.doi.org/10.1007/s13659-023-00421-z