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Application of human platelet lysate in chondrocyte expansion promotes chondrogenic phenotype and slows senescence progression via BMP–TAK1–p38 pathway

Osteoarthritis (OA) is one of the most common musculoskeletal degenerative. OA treatments are aiming to slow down disease progression; however, lack of cartilage regeneration efficacy. Autologous chondrocyte implantation (ACI) is a promising cartilage-regeneration strategy that uses human articular...

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Detalles Bibliográficos
Autores principales: Chitchongyingcharoen, Narong, Tawonsawatruk, Tulyapruek, Phetfong, Jitrada, Aroontanee, Wrattya, Supokawej, Aungkura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689743/
https://www.ncbi.nlm.nih.gov/pubmed/38036641
http://dx.doi.org/10.1038/s41598-023-48544-0