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Building a eukaryotic chromosome arm by de novo design and synthesis

The genome of an organism is inherited from its ancestor and continues to evolve over time, however, the extent to which the current version could be altered remains unknown. To probe the genome plasticity of Saccharomyces cerevisiae, here we replace the native left arm of chromosome XII (chrXIIL) w...

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Detalles Bibliográficos
Autores principales: Jiang, Shuangying, Luo, Zhouqing, Wu, Jie, Yu, Kang, Zhao, Shijun, Cai, Zelin, Yu, Wenfei, Wang, Hui, Cheng, Li, Liang, Zhenzhen, Gao, Hui, Monti, Marco, Schindler, Daniel, Huang, Linsen, Zeng, Cheng, Zhang, Weimin, Zhou, Chun, Tang, Yuanwei, Li, Tianyi, Ma, Yingxin, Cai, Yizhi, Boeke, Jef D., Zhao, Qiao, Dai, Junbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689750/
https://www.ncbi.nlm.nih.gov/pubmed/38036514
http://dx.doi.org/10.1038/s41467-023-43531-5