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Building a eukaryotic chromosome arm by de novo design and synthesis
The genome of an organism is inherited from its ancestor and continues to evolve over time, however, the extent to which the current version could be altered remains unknown. To probe the genome plasticity of Saccharomyces cerevisiae, here we replace the native left arm of chromosome XII (chrXIIL) w...
Autores principales: | Jiang, Shuangying, Luo, Zhouqing, Wu, Jie, Yu, Kang, Zhao, Shijun, Cai, Zelin, Yu, Wenfei, Wang, Hui, Cheng, Li, Liang, Zhenzhen, Gao, Hui, Monti, Marco, Schindler, Daniel, Huang, Linsen, Zeng, Cheng, Zhang, Weimin, Zhou, Chun, Tang, Yuanwei, Li, Tianyi, Ma, Yingxin, Cai, Yizhi, Boeke, Jef D., Zhao, Qiao, Dai, Junbiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689750/ https://www.ncbi.nlm.nih.gov/pubmed/38036514 http://dx.doi.org/10.1038/s41467-023-43531-5 |
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