Cancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection

Cell-free DNA (cfDNA) sequencing has demonstrated great potential for early cancer detection. However, most large-scale studies have focused only on either targeted methylation sites or whole-genome sequencing, limiting comprehensive analysis that integrates both epigenetic and genetic signatures. I...

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Detalles Bibliográficos
Autores principales: Kim, Su Yeon, Jeong, Seongmun, Lee, Wookjae, Jeon, Yujin, Kim, Yong-Jin, Park, Seowoo, Lee, Dongin, Go, Dayoung, Song, Sang-Hyun, Lee, Sanghoo, Woo, Hyun Goo, Yoon, Jung-Ki, Park, Young Sik, Kim, Young Tae, Lee, Se-Hoon, Kim, Kwang Hyun, Lim, Yoojoo, Kim, Jin-Soo, Kim, Hwang-Phill, Bang, Duhee, Kim, Tae-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689759/
https://www.ncbi.nlm.nih.gov/pubmed/37907748
http://dx.doi.org/10.1038/s12276-023-01119-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689759/
https://www.ncbi.nlm.nih.gov/pubmed/37907748
http://dx.doi.org/10.1038/s12276-023-01119-5

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