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Ketohexokinase-dependent metabolism of cerebral endogenous fructose in microglia drives diabetes-associated cognitive dysfunction

Dementia, as an advanced diabetes-associated cognitive dysfunction (DACD), has become the second leading cause of death among diabetes patients. Given that little guidance is currently available to address the DACD process, it is imperative to understand the underlying mechanisms and screen out spec...

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Detalles Bibliográficos
Autores principales: Li, Yansong, Jiang, Tao, Du, Mengyu, He, Shuxuan, Huang, Ning, Cheng, Bo, Yan, Chaoying, Tang, Wenxin, Gao, Wei, Guo, Hongyan, Li, Qiao, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689812/
https://www.ncbi.nlm.nih.gov/pubmed/37907746
http://dx.doi.org/10.1038/s12276-023-01112-y