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Single-cell characterization of macrophages in uveal melanoma uncovers transcriptionally heterogeneous subsets conferring poor prognosis and aggressive behavior

Uveal melanoma (UM) is the most frequent primary intraocular malignancy with high metastatic potential and poor prognosis. Macrophages represent one of the most abundant infiltrating immune cells with diverse functions in cancers. However, the cellular heterogeneity and functional diversity of macro...

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Detalles Bibliográficos
Autores principales: Li, Ke, Sun, Lanfang, Wang, Yanan, Cen, Yixin, Zhao, Jingting, Liao, Qianling, Wu, Wencan, Sun, Jie, Zhou, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689813/
https://www.ncbi.nlm.nih.gov/pubmed/37907747
http://dx.doi.org/10.1038/s12276-023-01115-9