Cargando…

Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies

Therapeutic antibodies are widely used to treat severe diseases. Most of them alter immune cells and act within the immunological synapse; an essential cell-to-cell interaction to direct the humoral immune response. Although many antibody designs are generated and evaluated, a high-throughput tool f...

Descripción completa

Detalles Bibliográficos
Autores principales: Shetab Boushehri, Sayedali, Essig, Katharina, Chlis, Nikolaos-Kosmas, Herter, Sylvia, Bacac, Marina, Theis, Fabian J., Glasmacher, Elke, Marr, Carsten, Schmich, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689847/
https://www.ncbi.nlm.nih.gov/pubmed/38036503
http://dx.doi.org/10.1038/s41467-023-43429-2