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Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies
Therapeutic antibodies are widely used to treat severe diseases. Most of them alter immune cells and act within the immunological synapse; an essential cell-to-cell interaction to direct the humoral immune response. Although many antibody designs are generated and evaluated, a high-throughput tool f...
Autores principales: | Shetab Boushehri, Sayedali, Essig, Katharina, Chlis, Nikolaos-Kosmas, Herter, Sylvia, Bacac, Marina, Theis, Fabian J., Glasmacher, Elke, Marr, Carsten, Schmich, Fabian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689847/ https://www.ncbi.nlm.nih.gov/pubmed/38036503 http://dx.doi.org/10.1038/s41467-023-43429-2 |
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