MicroRNA-93 promotes the pathogenesis of glaucoma by inhibiting matrix metalloproteinases as well as up-regulating extracellular matrix and Rho/ROCK signaling pathways

OBJECTIVE: To investigate the effect and potential molecular mechanism of microRNA-93 (miR-93) on retinal ganglion cells (RGCs) apoptosis as well as retinal damage in acute glaucoma mice. METHODS: RGCs apoptosis were induced by oxygen-glucose deprivation and reperfusion (OGD/R). The pro-apoptotic ef...

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Detalles Bibliográficos
Autores principales: Xu, Manhua, Wang, Yanxi, Zhou, Juan, Zhang, Xun, Yu, Yinggui, Li, Kaiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689882/
https://www.ncbi.nlm.nih.gov/pubmed/38045197
http://dx.doi.org/10.1016/j.heliyon.2023.e22012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689882/
https://www.ncbi.nlm.nih.gov/pubmed/38045197
http://dx.doi.org/10.1016/j.heliyon.2023.e22012

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