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MicroRNA-93 promotes the pathogenesis of glaucoma by inhibiting matrix metalloproteinases as well as up-regulating extracellular matrix and Rho/ROCK signaling pathways
OBJECTIVE: To investigate the effect and potential molecular mechanism of microRNA-93 (miR-93) on retinal ganglion cells (RGCs) apoptosis as well as retinal damage in acute glaucoma mice. METHODS: RGCs apoptosis were induced by oxygen-glucose deprivation and reperfusion (OGD/R). The pro-apoptotic ef...
Autores principales: | Xu, Manhua, Wang, Yanxi, Zhou, Juan, Zhang, Xun, Yu, Yinggui, Li, Kaiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689882/ https://www.ncbi.nlm.nih.gov/pubmed/38045197 http://dx.doi.org/10.1016/j.heliyon.2023.e22012 |
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