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Swedish multicentre study of target attainments with β-lactams in the ICU: which MIC parameter should be used?

BACKGROUND: Therapeutic drug monitoring (TDM) has been suggested to optimize antimicrobial target attainment, typically using 100%T(>MIC), in β-lactam treatment in the ICU. The MIC parameter used in this equation is mostly the worst case scenario MIC (MIC(WCS))—the highest MIC the empirical treat...

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Detalles Bibliográficos
Autores principales: Smekal, Anna-Karin, Furebring, Mia, Lipcsey, Miklos, Giske, Christian G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689903/
https://www.ncbi.nlm.nih.gov/pubmed/37897332
http://dx.doi.org/10.1093/jac/dkad327