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The non-specific lethal complex regulates genes and pathways genetically linked to Parkinson’s disease

Genetic variants conferring risks for Parkinson’s disease have been highlighted through genome-wide association studies, yet exploration of their specific disease mechanisms is lacking. Two Parkinson’s disease candidate genes, KAT8 and KANSL1, identified through genome-wide studies and a PINK1-mitop...

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Detalles Bibliográficos
Autores principales: Hicks, Amy R, Reynolds, Regina H, O’Callaghan, Benjamin, García-Ruiz, Sonia, Gil-Martínez, Ana Luisa, Botía, Juan, Plun-Favreau, Hélène, Ryten, Mina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689904/
https://www.ncbi.nlm.nih.gov/pubmed/37522749
http://dx.doi.org/10.1093/brain/awad246