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Neuromelanin accumulation drives endogenous synucleinopathy in non-human primates

Although neuromelanin is a dark pigment characteristic of dopaminergic neurons in the human substantia nigra pars compacta, its potential role in the pathogenesis of Parkinson’s disease (PD) has often been neglected since most commonly used laboratory animals lack neuromelanin. Here we took advantag...

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Detalles Bibliográficos
Autores principales: Chocarro, Julia, Rico, Alberto J, Ariznabarreta, Goiaz, Roda, Elvira, Honrubia, Adriana, Collantes, María, Peñuelas, Iván, Vázquez, Alfonso, Rodríguez-Pérez, Ana I, Labandeira-García, José L, Vila, Miquel, Lanciego, José L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689915/
https://www.ncbi.nlm.nih.gov/pubmed/37769648
http://dx.doi.org/10.1093/brain/awad331