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TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport

Accurate intracellular cholesterol traffic plays crucial roles. Niemann Pick type C (NPC) proteins NPC1 and NPC2, are two lysosomal cholesterol transporters that mediate the cholesterol exit from lysosomes. However, other proteins involved in this process remain poorly defined. Here, we find that th...

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Detalles Bibliográficos
Autores principales: Zhao, Nan, Deng, Gang, Yuan, Pei-Xin, Zhang, Ya-Fen, Jiang, Lu-Yi, Zhao, Xiaolu, Song, Bao-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689955/
https://www.ncbi.nlm.nih.gov/pubmed/37890669
http://dx.doi.org/10.1016/j.jlr.2023.100465