Cargando…
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport
Accurate intracellular cholesterol traffic plays crucial roles. Niemann Pick type C (NPC) proteins NPC1 and NPC2, are two lysosomal cholesterol transporters that mediate the cholesterol exit from lysosomes. However, other proteins involved in this process remain poorly defined. Here, we find that th...
Autores principales: | Zhao, Nan, Deng, Gang, Yuan, Pei-Xin, Zhang, Ya-Fen, Jiang, Lu-Yi, Zhao, Xiaolu, Song, Bao-Liang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689955/ https://www.ncbi.nlm.nih.gov/pubmed/37890669 http://dx.doi.org/10.1016/j.jlr.2023.100465 |
Ejemplares similares
-
Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6
por: Qian, Lydia, et al.
Publicado: (2023) -
Correlation between small and dense low‐density lipoprotein cholesterol and cardiovascular events in Beijing community population
por: Wang, Xiaona, et al.
Publicado: (2021) -
SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6
por: Fowler, Joseph Wayne M., et al.
Publicado: (2023) -
Identification of a Golgi-localized UDP-N-acetylglucosamine transporter in Trypanosoma cruzi
por: Baptista, Carlos Gustavo, et al.
Publicado: (2015) -
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine
por: Cao, Jiani, et al.
Publicado: (2022)