Untargeted metabolomics identifies metabolic dysregulation of sphingolipids associated with aggressive chronic lymphocytic leukaemia and poor survival

BACKGROUND: Metabolic dependencies of chronic lymphocytic leukaemia (CLL) cells may represent new personalized treatment approaches in patients harbouring unfavourable features. METHODS: Here, we used untargeted metabolomics and lipidomics analyses to isolate metabolomic features associated with agg...

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Detalles Bibliográficos
Autores principales: Nguyen Van Long, Flora, Valcourt‐Gendron, Délya, Caron, Patrick, Rouleau, Michèle, Villeneuve, Lyne, Simonyan, David, Le, Trang, Sergerie, Roxanne, Laverdière, Isabelle, Vanura, Katrina, Guillemette, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689972/
https://www.ncbi.nlm.nih.gov/pubmed/38037464
http://dx.doi.org/10.1002/ctm2.1442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689972/
https://www.ncbi.nlm.nih.gov/pubmed/38037464
http://dx.doi.org/10.1002/ctm2.1442

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