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Selective cargo sorting in stem cell‐derived small extracellular vesicles: impact on therapeutic efficacy for intervertebral disc degeneration

BACKGROUND: Growing evidence has suggested the role of stem cell‐derived small extracellular vesicles (sEVs) in intervertebral disc degeneration (IVDD). The cargo sorting of sEVs, particularly miRNAs, may be influenced when the donor cell is subjected to oxidative stress. Here, we discovered that mi...

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Detalles Bibliográficos
Autores principales: Liao, Zhiwei, Tong, Bide, Zhang, Xiaoguang, Zhang, Weifeng, Ke, Wencan, Liang, Huaizhen, Lei, Ming, Hua, Wenbin, Li, Shuai, Song, Yu, Wu, Xinghuo, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10689973/
https://www.ncbi.nlm.nih.gov/pubmed/38037469
http://dx.doi.org/10.1002/ctm2.1494