Distinct tau folds initiate templated seeding and alter the post-translational modification profile

Pathological tau accumulates in the brain in tauopathies such as Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration, and forms amyloid-like filaments incorporating various post-translational modifications (PTMs). Cryo-electron microscopic (cry...

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Detalles Bibliográficos
Autores principales: Tarutani, Airi, Kametani, Fuyuki, Tahira, Marina, Saito, Yuko, Yoshida, Mari, Robinson, Andrew C, Mann, David M A, Murayama, Shigeo, Tomita, Taisuke, Hasegawa, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690015/
https://www.ncbi.nlm.nih.gov/pubmed/37904205
http://dx.doi.org/10.1093/brain/awad272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690015/
https://www.ncbi.nlm.nih.gov/pubmed/37904205
http://dx.doi.org/10.1093/brain/awad272

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