Cargando…

Distinct tau folds initiate templated seeding and alter the post-translational modification profile

Pathological tau accumulates in the brain in tauopathies such as Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration, and forms amyloid-like filaments incorporating various post-translational modifications (PTMs). Cryo-electron microscopic (cry...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tarutani, Airi, Kametani, Fuyuki, Tahira, Marina, Saito, Yuko, Yoshida, Mari, Robinson, Andrew C, Mann, David M A, Murayama, Shigeo, Tomita, Taisuke, Hasegawa, Masato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690015/ https://www.ncbi.nlm.nih.gov/pubmed/37904205 http://dx.doi.org/10.1093/brain/awad272

Ejemplares similares

Human tauopathy-derived tau strains determine the substrates recruited for templated amplification
por: Tarutani, Airi, et al.
Publicado: (2021)

Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau
por: Taniguchi-Watanabe, Sayuri, et al.
Publicado: (2015)

Cryo‐EM structures of tau filaments from SH‐SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration
por: Tarutani, Airi, et al.
Publicado: (2023)

Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43
por: Tarutani, Airi, et al.
Publicado: (2022)

Correction to: Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43
por: Tarutani, Airi, et al.
Publicado: (2022)

Comparison of Common and Disease-Specific Post-translational Modifications of Pathological Tau Associated With a Wide Range of Tauopathies
por: Kametani, Fuyuki, et al.
Publicado: (2020)

Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy
por: Lövestam, Sofia, et al.
Publicado: (2021)

Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains
por: Kametani, Fuyuki, et al.
Publicado: (2016)

Novel tau filament fold in corticobasal degeneration
por: Zhang, Wenjuan, et al.
Publicado: (2020)

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
por: Kametani, Fuyuki, et al.
Publicado: (2018)

Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer’s disease brain
por: Dan, Ayaho, et al.
Publicado: (2013)

Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods
por: Tarutani, Airi, et al.
Publicado: (2018)

3R and 4R tau isoforms in paired helical filaments in Alzheimer’s disease
por: Hasegawa, Masato, et al.
Publicado: (2013)

Extracellular association of APP and tau fibrils induces intracellular aggregate formation of tau
por: Takahashi, Muneaki, et al.
Publicado: (2015)

Colocalization of BRCA1 with Tau Aggregates in Human Tauopathies
por: Kurihara, Masanori, et al.
Publicado: (2019)

Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer’s disease
por: Mano, Tatsuo, et al.
Publicado: (2017)

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments
por: Kaniyappan, Senthilvelrajan, et al.
Publicado: (2020)

N-Methyl-D-Aspartate Receptor Link to the MAP Kinase Pathway in Cortical and Hippocampal Neurons and Microglia Is Dependent on Calcium Sensors and Is Blocked by α-Synuclein, Tau, and Phospho-Tau in Non-transgenic and Transgenic APP(Sw,Ind) Mice
por: Franco, Rafael, et al.
Publicado: (2018)

TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
por: Arseni, Diana, et al.
Publicado: (2023)

Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β
por: Nies, Sarah Helena, et al.
Publicado: (2021)

Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold
por: Qi, Chao, et al.
Publicado: (2023)

Protection against Amyloid-β Oligomer Neurotoxicity by Small Molecules with Antioxidative Properties: Potential for the Prevention of Alzheimer’s Disease Dementia
por: Araki, Wataru, et al.
Publicado: (2022)

Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein
por: Toto, Angelo, et al.
Publicado: (2016)

Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice
por: Stancu, Ilie-Cosmin, et al.
Publicado: (2015)

Tau and TDP-43 accumulation of the basal nucleus of Meynert in individuals with cerebral lobar infarcts or hemorrhage
por: Hatsuta, Hiroyuki, et al.
Publicado: (2019)

Propagation of pathological α-synuclein in marmoset brain
por: Shimozawa, Aki, et al.
Publicado: (2017)

Tau and Membranes: Interactions That Promote Folding and Condensation
por: Sallaberry, Chad A., et al.
Publicado: (2021)

Prion-Like Seeding of Misfolded α-Synuclein in the Brains of Dementia with Lewy Body Patients in RT-QUIC
por: Sano, Kazunori, et al.
Publicado: (2017)

Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43
por: Tanaka, Yoshinori, et al.
Publicado: (2023)

Template Directed Reversible Photochemical Ligation of Oligodeoxynucleotides
por: Nakamura, Shigetaka, et al.
Publicado: (2011)

Age-dependent formation of TMEM106B amyloid filaments in human brains
por: Schweighauser, Manuel, et al.
Publicado: (2022)

Casein kinase 1δ/ε phosphorylates fused in sarcoma (FUS) and ameliorates FUS-mediated neurodegeneration
por: Kishino, Yuya, et al.
Publicado: (2022)

The pathological and biochemical identification of possible seed‐lesions of transmitted transthyretin amyloidosis after domino liver transplantation
por: Yoshinaga, Tsuneaki, et al.
Publicado: (2016)

Prion-Seeding Activity Is widely Distributed in Tissues of Sporadic Creutzfeldt-Jakob Disease Patients
por: Takatsuki, Hanae, et al.
Publicado: (2016)

Primitive templated catalysis of a peptide ligation by self-folding RNAs
por: Kashiwagi, Norimasa, et al.
Publicado: (2009)

Modularity of Protein Folds as a Tool for Template-Free Modeling of Structures
por: Vallat, Brinda, et al.
Publicado: (2015)

Network of hotspot interactions cluster tau amyloid folds
por: Mullapudi, Vishruth, et al.
Publicado: (2023)

Appropriate usage of food thickening agents to prevent non-disintegration of magnesium oxide tablets
por: Matsuo, Taisuke, et al.
Publicado: (2020)

RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth
por: Dinkel, Paul D., et al.
Publicado: (2015)

Templated α-Synuclein Inclusion Formation Is Independent of Endogenous Tau
por: Stoyka, Lindsay E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_730a3iuhl761nht3kg6caj62uk