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Restoring neuronal chloride extrusion reverses cognitive decline linked to Alzheimer’s disease mutations
Disinhibition during early stages of Alzheimer's disease is postulated to cause network dysfunction and hyperexcitability leading to cognitive deficits. However, the underlying molecular mechanism remains unknown. Here we show that, in mouse lines carrying Alzheimer's disease-related mutat...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690023/ https://www.ncbi.nlm.nih.gov/pubmed/37551444 http://dx.doi.org/10.1093/brain/awad250 |