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How should we be using biomarkers in trials of disease modification in Parkinson’s disease?

The recent validation of the α-synuclein seed amplification assay as a biomarker with high sensitivity and specificity for the diagnosis of Parkinson’s disease has formed the backbone for a proposed staging system for incorporation in Parkinson’s disease clinical studies and trials. The routine use...

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Detalles Bibliográficos
Autores principales: Vijiaratnam, Nirosen, Foltynie, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690028/
https://www.ncbi.nlm.nih.gov/pubmed/37536279
http://dx.doi.org/10.1093/brain/awad265