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The role of angiotensin receptor blocker (losartan) on decreasing fibrotic process of corpora cavernosa in priapism model of wistar rats

Background: Priapism induces regulation of Transforming Growth Factor-β1 (TGF-β1) expression and collagen-type-1 deposition. This will replace the normal corpora cavernosa with fibrotic tissue which eventually resulted in erectile dysfunction. It is also known that the fibrosis process of corpora ca...

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Detalles Bibliográficos
Autores principales: Siregar, Safendra, Rulianov, Rulianov, Ksatriapraja, Rangga Adhazi, Stefanus, Dicky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690033/
https://www.ncbi.nlm.nih.gov/pubmed/38046538
http://dx.doi.org/10.12688/f1000research.123040.2