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m(6)A-Mediated Biogenesis of circDDIT4 Inhibits Prostate Cancer Progression by Sequestrating ELAVL1/HuR

The pathologic significance of the circular RNA DDIT4 (circDDIT4), which is formed by backsplicing at the 3′-untranslated region (UTR) with a 5′ splice acceptor site in exon 2 of linear DDIT4 mRNA, has yet to be determined. Our study found that circDDIT4 is downregulated in prostate cancer and funct...

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Detalles Bibliográficos
Autores principales: Kong, Zhe, Lu, Yali, Yang, Yue, Chang, Kun, Lin, Yan, Huang, Yan, Wang, Chenji, Zhang, Lu, Xu, Wei, Zhao, Shimin, Li, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690048/
https://www.ncbi.nlm.nih.gov/pubmed/37647111
http://dx.doi.org/10.1158/1541-7786.MCR-22-0271