The katanin A-subunits KATNA1 and KATNAL1 act co-operatively in mammalian meiosis and spermiogenesis to achieve male fertility

Katanins, a class of microtubule-severing enzymes, are potent M-phase regulators in oocytes and somatic cells. How the complex and evolutionarily crucial, male mammalian meiotic spindle is sculpted remains unknown. Here, using multiple single and double gene knockout mice, we reveal that the canonic...

Descripción completa

Detalles Bibliográficos
Autores principales: Dunleavy, Jessica E. M., Graffeo, Maddison, Wozniak, Kathryn, O'Connor, Anne E., Merriner, D. Jo, Nguyen, Joseph, Schittenhelm, Ralf B., Houston, Brendan J., O'Bryan, Moira K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690054/
https://www.ncbi.nlm.nih.gov/pubmed/37882691
http://dx.doi.org/10.1242/dev.201956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690054/
https://www.ncbi.nlm.nih.gov/pubmed/37882691
http://dx.doi.org/10.1242/dev.201956

Ejemplares similares