Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania

Attempts to inactivate an essential gene in the protozoan parasite Leishmania have often led to the generation of extra copies of the wild-type alleles of the gene. In experiments with Leishmania tarentolae set up to disrupt the gene encoding the J-binding protein 1 (JBP1), a protein binding to the...

Descripción completa

Detalles Bibliográficos
Autores principales: Genest, Paul-André, ter Riet, Bas, Dumas, Carole, Papadopoulou, Barbara, van Luenen, Henri G. A. M., Borst, Piet
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069007/
https://www.ncbi.nlm.nih.gov/pubmed/15781496
http://dx.doi.org/10.1093/nar/gki304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069007/
https://www.ncbi.nlm.nih.gov/pubmed/15781496
http://dx.doi.org/10.1093/nar/gki304

Ejemplares similares