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Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania
Attempts to inactivate an essential gene in the protozoan parasite Leishmania have often led to the generation of extra copies of the wild-type alleles of the gene. In experiments with Leishmania tarentolae set up to disrupt the gene encoding the J-binding protein 1 (JBP1), a protein binding to the...
Autores principales: | Genest, Paul-André, ter Riet, Bas, Dumas, Carole, Papadopoulou, Barbara, van Luenen, Henri G. A. M., Borst, Piet |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069007/ https://www.ncbi.nlm.nih.gov/pubmed/15781496 http://dx.doi.org/10.1093/nar/gki304 |
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