SGN-B6A: A New Vedotin Antibody–Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications

Integrin beta-6, a component of the heterodimeric adhesion receptor alpha-v/beta-6, is overexpressed in numerous solid tumors. Its expression has been shown by multiple investigators to be a negative prognostic indicator in diverse cancers including colorectal, non–small cell lung, gastric, and cerv...

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Detalles Bibliográficos
Autores principales: Lyon, Robert P., Jonas, Mechthild, Frantz, Christopher, Trueblood, Esther S., Yumul, Roma, Westendorf, Lori, Hale, Christopher J., Stilwell, Jackie L., Yeddula, Narayana, Snead, Katie M., Kumar, Vineet, Patilea-Vrana, Gabriela I., Klussman, Kerry, Ryan, Maureen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Large Molecule Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690100/
https://www.ncbi.nlm.nih.gov/pubmed/37619980
http://dx.doi.org/10.1158/1535-7163.MCT-22-0817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690100/
https://www.ncbi.nlm.nih.gov/pubmed/37619980
http://dx.doi.org/10.1158/1535-7163.MCT-22-0817

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